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Article title: MicroRNAs: back to basics
Author name(s): Charles H Lawrie
Journal: Myeloid & Lymphoid disorders in practice
Issue: September 2012, Volume 6 Number 2
Pages: 3-5
Intro: Despite being only formally recognised for just over ten years, microRNAs (miRNAs) have emerged as one of the hottest subjects in biology in recent times. There is now overwhelming evidence that miRNAs play a fundamental role in many, if not all, physiological and disease processes, including myeloid disorders. This review will give a brief overview of this field, focusing on the involvement and potential clinical significance of miRNAs in the myeloid malignancies acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS).